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Ageing is a complicated process involving the interaction of numerous biological factors with the external environment. Along with inevitability, it is the transient and elusive characteristics of ageing that frequently capture attention. Most of us will know someone who appears ten, even twenty years younger than their chronological age. It also seems true that profoundly stressful or sad life events have a potential to age those afflicted, sometimes dramatically and with physical changes that seem to occur overnight. From the perspective of this humble reality, it is wise to ignore and avoid cosmetic products and procedures which promise to eradicate or reverse the visible effects of skin damage and ageing. The concept of eternal youth is...